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CP-802079 hydrochloride hydrate

品牌
Sigma-Aldrich
CAS
736175-49-8
货号
PZ0148
规格纯度
≥98% (HPLC)
参考价格
1434.12 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.

特点和优势

This compound is featured on the Glycine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式C22H21ClN2O4S · xHCl · yH2O
分子量444.93 (anhydrous free base basis)
MDL编号MFCD18452850
PubChem化学物质编号329823733
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
manufacturer/tradenamePfizer®
颜色very light brown
溶解性DMSO: ≥20 mg/mL
创始人Pfizer
储存温度2-8℃
SMILES stringO.Cl.CN(CCC(Oc1ccc(cc1)C(=O)c2nccs2)c3ccc(Cl)cc3)CC(O)=O
InChI1S/C22H21ClN2O4S.ClH.H2O/c1-25(14-20(26)27)12-10-19(15-2-6-17(23)7-3-15)29-18-8-4-16(5-9-18)21(28)22-24-11-13-30-22;;/h2-9,11,13,19H,10,12,14H2,1H3,(H,26,27);1H;1H2
InChI keyCVQXAUBKPDYXHF-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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