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cis-22a

品牌
Sigma-Aldrich
CAS
1819366-84-1
货号
SML3112
规格纯度
≥98% (HPLC)
参考价格
1179.67 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

cis-22a is a potent and highly selective TrpV6 (CaT1, ECaC2) inhibitor (Cd2+ influx IC50 = 320 nM; hTRPV6 transfected HEK293) with much reduced and little potency against other calcium channels and related TRP targets. cis-22a selectively inhibits the growth of TrpV6-expressing breast cancer T47D (IC50 = 25 μM), but not TrpV6-negative ovarian carcinoma SKOV3 cultures (IC50 >50 μM).

基本信息

经验(实验)分子式C22H29N3 · 2CF3CO2H
分子量563.53

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性H2O: 2 mg/mL, clear
储存温度2-8℃
SMILES stringCC1=CC=CC([C@H]2CC[C@@H](N3CCN(C4=CN=CC=C4)CC3)CC2)=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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