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ARL-17477 dihydrochloride hydrate

品牌
Sigma-Aldrich
CAS
866914-87-6
货号
SML0178
包装型号
规格纯度
≥98% (HPLC)
参考价格
1526.64 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

ARL-17477 dihydrochloride hydrate may be used in cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

ARL-17477 is an nNOS specific inhibitor. The IC50 against rat nNOS is 35 nM and it has 100-fold selectivity over endothelial and inducible isoforms. ARL-17477 penetrates the brain, and reduces infarct size and reduces cerebral blood flow in several different rodent models of ischemic brain injury.

特点和优势

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C20H20ClN3S·2HCl · xH2O
分子量442.83 (anhydrous basis)
MDL编号MFCD21608518
PubChem化学物质编号329825207

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性H2O: ≥5 mg/mL
创始人AstraZeneca
储存温度2-8℃
SMILES stringO.Cl.Cl.Clc1cccc(CNCCc2ccc(NC(=N)c3cccs3)cc2)c1
InChI1S/C20H20ClN3S.2ClH.H2O/c21-17-4-1-3-16(13-17)14-23-11-10-15-6-8-18(9-7-15)24-20(22)19-5-2-12-25-19;;;/h1-9,12-13,23H,10-11,14H2,(H2,22,24);2*1H;1H2
InChI keyQOPATWWWZNTSQF-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H319
预防措施声明P301 + P312 + P330 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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