产品介绍：
产品说明
生化/生理作用
AGF347 is a potent inhibitor of serine hydroxymethyltransferase 2 (SHMT2) that inhibits mitochondrial C1 metabolism. It also inhibits cytosolic C1 targets such as SHMT1, GARFTase, and AICARFTase. AGF347 inhibits de novo purine biosynthesis. AGF347 exhibits potent broad spectrum in vitro and in vivo antitumor efficacy.
基本信息
| 经验(实验)分子式 | C22H24FN5O6 |
| 分子量 | 473.45 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/L, clear |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(CC[C@H](NC(C1=CC=C(C=C1F)CCCCN2C=CC(N=C(N3)N)=C2C3=O)=O)C(O)=O)O |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
