产品介绍：
产品说明
应用
PJ-34 hydrochloride hydrate has been used:
- as a poly(ADP-ribose) polymerase (PARP) inhibitor 1 in rats to test the effect of PAPR1 in neuropathic pain
- as a component of protein extraction buffer to enable visualization of the high-molecular-weight smear of PARylated proteins in various cell samples
- as PARP inhibitor in murine MLE-12 epithelial cell line
包装
5 mg in glass bottle
生化/生理作用
PJ-34 is a prototypic poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor.
PJ-34是一种强效聚(ADP-核糖)聚合酶(PARP)抑制剂。
基本信息
| 经验(实验)分子式 | C17H17N3O2 · HCl · xH2O |
| 分子量 | 331.80 (anhydrous basis) |
| PubChem化学物质编号 | 24898531 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to yellow |
| 溶解性 | H2O: 22 mg/mL |
| SMILES string | Cl[H].[H]O[H].CN(C)CC(=O)Nc1ccc2NC(=O)c3ccccc3-c2c1 |
| InChI | 1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2 |
| InChI key | YCALIZUKAFUQCH-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
