产品说明
一般描述
3-Methyl-2-oxindole (MOI) is a 3-substituted-2-oxindole. It is reported to be formed during the oxidation of indole-3-acetic acid in the presence of FeII under aerobic conditions. MOI undergoes asymmetric anti-Mannich-type reaction with N-tosyl aryl aldimines in the presence of alkaloid cinchona derivatives to form anti-3,3-disubsituted 2-oxindole derivatives. It also undergoes asymmetric hydroxyamination with nitrosoarenes to form N-nitroso aldol products.
应用
3-Methyl-2-oxindole may be used in the preparation of 3-hydroxy-3-methyl-2-oxindole.
- Reactant for enantioselective α-amination reactions
- Reactant for aldol reaction with glyoxal derivatives
- Reactant for amine thiourea catalyzed conjugate addition to α,β-unsaturated aldehydes
- Reactant for O-acetylation reactions
- Reactant for preparation of a disubstituted oxoindole by using rhodium-catalyzed cyclopropanation/ring-opening reactions
包装
5, 25 g in glass bottle
基本信息
经验(实验)分子式 | C9H9NO |
分子量 | 147.17 |
MDL编号 | MFCD04037370 |
PubChem化学物质编号 | 24872867 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | 96% |
mp | 117-121 ℃ (lit.) |
SMILES string | CC1C(=O)Nc2ccccc12 |
InChI | 1S/C9H9NO/c1-6-7-4-2-3-5-8(7)10-9(6)11/h2-6H,1H3,(H,10,11) |
InChI key | BBZCPUCZKLTAJQ-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |