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AH6809

品牌
Sigma-Aldrich
CAS
33458-93-4
货号
A1221
规格纯度
≥98%, crystalline solid or supercooled liquid
参考价格
1249.07 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

AH6809 has been used:

  • as a prostaglandin E2 receptor 1 & 2 (EP1/2) antagonist to analyze its effects on cyclooxygenase-2 /prostaglandin E2 (COX-2/PGE2) signaling in the angiogenic feedback of endothelial cells to hypoxia
  • as an EP2 antagonist to study its effects on tumor angiogenesis in human prostate cancer cell lines
  • as an EP2 antagonist to analyze its effects on overexpression of amyloid precursor protein (APP)

包装

5 mg in glass bottle

生化/生理作用

AH6809 plays a role in antagonizing the proliferation of non-small cell lung cancer cell lines.
DP/EP prostanoid receptor antagonist; has the highest affinity for DP receptors, but also acts as a weak antagonist at murine EP1 and EP2 prostanoid receptors.

特点和优势

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C17H14O5
分子量298.29
MDL编号MFCD08056083
PubChem化学物质编号329770690
NACRESNA.77

产品性质

质量水平100
测定≥98%
形式crystalline solid or supercooled liquid
溶解性ethanol: soluble 2.5 mg/mL
DMSO or DMF: soluble 8 mg/mL
SMILES stringCC(C)Oc1ccc2c(Oc3ccc(cc3C2=O)C(O)=O)c1
InChI1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
InChI keyAQFFXPQJLZFABJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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