产品说明
应用
Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures.
包装
5 mg in glass bottle
生化/生理作用
Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets.
Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A2.
特点和优势
This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
Hygroscopic, photosensitive, air sensitive
基本信息
经验(实验)分子式 | C21H31F3O |
分子量 | 356.47 |
MDL编号 | MFCD00236427 |
PubChem化学物质编号 | 24890647 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥97% (NMR) |
形式 | oil |
储存条件 | desiccated protect from light under inert gas |
颜色 | yellow |
溶解性 | DMSO: >5 mg/mL |
储存温度 | −20℃ |
SMILES string | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F |
InChI | 1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15- |
InChI key | PLWROONZUDKYKG-DOFZRALJSA-N |
Gene Information | human ... PLA2G1B(5319) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |