Safingol

产品介绍：

产品说明

一般描述

Safingol is a synthetic L-threo-stereoisomer of endogenous (D-erythro-) sphinganine. It acts as an inhibitor of protein kinase C and sphingosine kinase in vitro. Safingol is involved in ceramide generation and induction of apoptosis. It is known to stimulate antitumor activity of cisplatin.

应用

Safingol has been used as a substituent of dihydrosphingosine (dhSph) to increase the cytotoxic response in N-(4-hydroxyphenyl)retinamide (4-HPR)-resistant cells.

包装

5 mL Amber Glass Screw Cap Vial (860488P-5mg)

基本信息

经验(实验)分子式	C₁₈H₃₉NO₂
分子量	301.51
NACRES	NA.25

产品性质

形式	powder
包装	pkg of 1 × 5 mg (860488P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860488P
运输	dry ice
储存温度	−20℃
SMILES string	CCCCCCCCCCCCCCC[C@@](O)([H])[C@@]([H])(N)CO
InChI	1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3
InChI key	OTKJDMGTUTTYMP-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable