产品说明
Amino Acid Sequence
Z-Leu-Leu-Nle-al
一般描述
Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.
应用
γ Secretase Inhibitor has been used to study the suppressive miR-129 functions through inhibition on estrogen receptor 1 (ESR1) and NOTCH signaling in breast cancer stem cells.
基本信息
经验(实验)分子式 | C26H41N3O5 |
分子量 | 475.62 |
NACRES | NA.32 |
产品性质
测定 | ≥95% (HPLC) |
形式 | lyophilized |
组成 | Peptide Content, ≥85% |
储存条件 | protect from light |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |