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γ Secretase Inhibitor

品牌
Sigma-Aldrich
货号
SCP0004
包装型号
规格纯度
≥95% (HPLC)
参考价格
3157.63 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

Amino Acid Sequence

Z-Leu-Leu-Nle-al

一般描述

Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.

应用

γ Secretase Inhibitor has been used to study the suppressive miR-129 functions through inhibition on estrogen receptor 1 (ESR1) and NOTCH signaling in breast cancer stem cells.

基本信息

经验(实验)分子式C26H41N3O5
分子量475.62
NACRESNA.32

产品性质

测定≥95% (HPLC)
形式lyophilized
组成Peptide Content, ≥85%
储存条件protect from light
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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