产品说明
一般描述
F7-Cholesterol is a fluorinated derivative of cholesterol. It is a cholesterol analog. F7-Cholesterol is useful as helper lipid in conjunction with vectors for DNA transfection.
应用
F7-Cholesterol has been used:
- in the preparation of liposomes for DNA delivery studies
- to investigate its rescue functionality in hedgehog signaling in sterol-depleted cells
- in preparation of monolayers for pressure and area isotherms studies
生化/生理作用
F7-Cholesterol has potential biological applications. It has a negative dipole moment. F7-Cholesterol rescues hedgehog signaling in sterol-depleted cells. The molecular orientation and phospholipid interaction of F7-cholesterol is similar to hydrogenated cholesterol.
包装
5 mL Amber Glass Screw Cap Vial (700002P-5mg)
基本信息
经验(实验)分子式 | C27H39OF7 |
分子量 | 512.59 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 5 mg (700002P-5mg) |
manufacturer/tradename | Avanti Polar Lipids 700002P |
运输 | dry ice |
储存温度 | −20℃ |
InChI | 1S/C27H39F7O/c1-16(5-4-12-25(28,26(29,30)31)27(32,33)34)20-8-9-21-19-7-6-17-15-18(35)10-13-23(17,2)22(19)11-14-24(20,21)3/h6,16,18-22,35H,4-5,7-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,23+,24-/m1/s1 |
InChI key | DUAIJEYNEJQOCE-OLSVQSNTSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |