产品说明
应用
Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
Saclofen has been used to prevent the inhibitory action of oxytocin on capsaicin-induced glutamatergic spontaneous excitatory transmission in rat neurons.
包装
5 mg in glass bottle
生化/生理作用
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
Saclofen is the sulphonic analog of baclofen and is a selective GABAB receptor antagonist.
基本信息
经验(实验)分子式 | C9H12ClNO3S |
分子量 | 249.71 |
MDL编号 | MFCD00216817 |
PubChem化学物质编号 | 329824485 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
形式 | solid |
颜色 | white |
溶解性 | 0.1 M NaOH: 20 mg/mL |
SMILES string | NCC(CS(O)(=O)=O)c1ccc(Cl)cc1 |
InChI | 1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14) |
InChI key | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
Gene Information | human ... GABBR1(2550), GABBR2(9568) mouse ... GABBR1(54393), GABBR2(242425) rat ... GABBR1(81657), GABBR2(83633) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |