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Nek6, Active human

品牌
Sigma-Aldrich
货号
N4662
规格纯度
recombinant, expressed in E. coli, ≥80% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
8640.83 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Kinase activity is measured as the molar amount of phosphate incorporated into myelin basic protein, per minute per mg protein at 30 ℃ using a final concentration of 50 μM [32P] ATP.

生化/生理作用

Nek6 is a nuclear and cytoplasmic kinase that is required for mitotic progression of human cells. It is phosphorylated and activated during M phase of the cell cycle. Inhibition of Nek6 arrests cells in M phase and triggers apoptosis, suggesting that Nek6 is required for metaphase-anaphase transition.

单位定义

One unit will incorporate 1 nanomole of phosphate into myelin basic protein (MBP) per minute at pH 7.2 at 30 deg C using a final concentration of 50 μm (32p) ATP

外形

Solution in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

基本信息

MDL编号MFCD07370972
NACRESNA.32

产品性质

质量水平100
重组expressed in E. coli
测定≥80% (SDS-PAGE)
形式buffered aqueous glycerol solution
enzyme activity≥10 units/mg protein
分子量protein apparent mol wt ~58 kDa
UniProt登记号Q9HC98
运输dry ice
储存温度−70℃
Gene Informationhuman ... NEK6(10783)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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