C4 Ceramide (d18:1/4:0)

产品介绍：

产品说明

一般描述

C4 Ceramide (d18:1/4:0) or N-butyroyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with butyric acid. It is a non-toxic, short-chain sphingolipid.

应用

C4 Ceramide (d18:1/4:0) has been used to study its role in rescuing and stabilizing ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).

生化/生理作用

C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF).

包装

5 mL Amber Glass Screw Cap Vial (860504P-5mg)

基本信息

经验(实验)分子式	C₂₂H₄₃NO₃
分子量	369.58
NACRES	NA.25

产品性质

形式	powder
包装	pkg of 1 × 5 mg (860504P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860504P
运输	dry ice
储存温度	−20℃
SMILES string	OC[C@]([H])(NC(CCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable