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12:0(2R-OH) Ceramide

品牌
Avanti
CAS
1246298-44-1
货号
860811P
规格纯度
N-(2′-(R)-hydroxylauroyl)-D-erythro-sphingosine, powder
参考价格
3207.48 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Ceramides containing 2-hydroxy fatty acid (hFA) are found primarily in the epidermis. 12:0(2R-OH) Ceramide is a 2R hydroxylated lauric acid-containing ceramide.

生化/生理作用

Hydroxy fatty acid (hFA)-sphingolipids play a specific role in cell signaling. Synthesis of hFA-ceramides requires fatty acid 2-hydroxylase (FA2H). Mutations of this key enzyme are associated with the development of nervous system disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for the epidermal permeability barrier function. The mechanism of action for an antitumor drug, PM02734 involves hFA-ceramides in the cell membrane.

包装

5 mL Amber Glass Screw Cap Vial (860811P-5mg)

基本信息

经验(实验)分子式C30H59NO4
分子量497.79
NACRESNA.25

产品性质

形式powder
包装pkg of 1 × 5 mg (860811P-5mg)
manufacturer/tradenameAvanti Polar Lipids 860811P
运输dry ice
储存温度−20℃
SMILES stringCCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCC)=O)CO

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

Sigma-Aldrich

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