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Thymidine Phosphorylase, recombinant from Escherichia coli

品牌
Sigma-Aldrich
CAS
9030-23-3
货号
SRE0006
规格纯度
recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500 units/mL
参考价格
8657.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5000 units in glass bottle

生化/生理作用

An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.

单位定义

One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃.

制备说明

Cloned from E. coli and produced in overexpressing E. coli

基本信息

酶学委员会(EC)编号2.4.2.4 ( BRENDA | IUBMB )
MDL编号MFCD00132426
NACRESNA.54

产品性质

重组expressed in E. coli
质量水平400
形式buffered aqueous solution
浓度≥500 units/mL
application(s)diagnostic assay manufacturing
运输wet ice
储存温度2-8℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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