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Monoclonal Anti-Monocyte Chemotactic Protein-2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
M8413
规格纯度
clone 35509.11, purified immunoglobulin, lyophilized powder
参考价格
4915.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monocyte Chemotactic Protein-2 (MCP-2) belongs to a family of C-C chemotactic cytokines. MCP-1, -3, -4, and -5 are the other five monocyte chemo attractants identified. The MCP cytokines are involved in recruitment of leukocytes to the sites of inflammation, and activate NK cells and CD4+ and CD8+ T lymphocytes. Additionally, MCP cytokines can activate basophils to secrete histamines and also attract eosinophils. MCPs play an important role in pathological conditions such as systemic sclerosis, myocardia and cardiac ischemia. Anti-monocyte chemotactic protein 2 antibody specifically reacts with human MCP-2. The antibody shows <20% cross reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

特异性

Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.

免疫原

recombinant human MCP-2 expressed in E. coli.

应用

Monoclonal Anti-Monocyte Chemotactic Protein-2 antibody may be used in ELISA at a concentration of 2.0 μg/ml. For immunoblotting a working concentration of 1-2 μg/ml may be used. The antibody is suitable for neutralization reactions; ND50 is 1-4 μg/ml.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose

制备说明

Purified using protein A.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01092422
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆35509.11, monoclonal
形式lyophilized powder
species reactivityhuman
technique(s)indirect ELISA: suitable
neutralization: suitable
western blot: suitable
同位素/亚型IgG1
UniProt登记号P80075
储存温度−20℃
Gene Informationhuman ... CCL8(6355)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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