产品说明
应用
Interleukin-4 from mouse has been used:
- as a component of cell culture media for class switch recombination assay
- to study its therapeutic benefits for mucosal healing
- as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)
生化/生理作用
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
外形
Lyophilized, 0.2 μm filtered, with no additives.
分析说明
The proliferative activity is tested in culture using mouse HT-2 cells.
基本信息
| MDL编号 | MFCD00166698 |
| NACRES | NA.77 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (SDS-PAGE) |
| 形式 | lyophilized powder |
| 效能 | 0.1-2.0 ng/mL ED50/EC50 |
| 质量 | endotoxin tested |
| 分子量 | ~13.5 kDa |
| 包装 | pkg of 5 μg |
| technique(s) | cell culture | mammalian: suitable |
| 杂质 | <0.1 EU/μg |
| UniProt登记号 | P07750 |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Il4(16189) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
