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Protein Kinase G Iβ human

品牌
Sigma-Aldrich
货号
P3738
规格纯度
≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, buffered aqueous glycerol solution
参考价格
9795.88 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Protein Kinase G is a serine/threonine-specific protein kinase that is activated by cGMP. Protein Kinase G Iβ is used to induce apoptosis and inhibit cell proliferation.

生化/生理作用

Protein Kinase G Iβ induces apoptosis in certain cell lines such as human breast cancer cell lines MCF-7 and MDA-MB-468. It inhibits cell proliferation and induces apoptosis in colon cancer cell lines.

单位定义

One unit will phosphorylate 1 micromole of VASPtide(RRKVSKQE) substrate per minute in 10 mM HEPES, pH 7.4, 5 mM MgCl2, 1 mM DTE and 0.2 mM EDTA.

外形

Solution in 20 mM Tris buffer, pH 7.4, 1 mM EDTA, 1 mM β-mercaptoethanol, 100 mM NaCl, 10 U/ml Trasylol, and 50% glycerol.

基本信息

酶学委员会(EC)编号2.7.11.12 ( BRENDA | IUBMB )
MDL编号MFCD03458230
NACRESNA.54

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
测定≥95% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity≥1.5 units/mg protein (20-fold stimulation by cGMP (5 μM))
分子量 76 kDa (monomer)
UniProt登记号Q13976
相关疾病cancer
运输wet ice
储存温度−20℃
Gene Informationhuman ... PRKG1(5592)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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