产品说明
一般描述
Oncostatin M (OSM) is a growth-regulating cytokine produced by the activated T lymphocytes and macrophages. It has a pivotal role in stimulating the production of IL-6 in cultured human endothelial cells. It also facilitates the LDL receptor expression and its uptake by hepatoma cells. Further, OSM can induce synovial fibroblast-like cells to produce urokinase type plasminogen activator. Monoclonal anti-Oncostatin M antibody can be used for neutralizing the biological activity of rhOSM on the human TF-1 cell line. Mouse anti-Oncostatin M antibody reacts specifically with recombinant human OSM. The product has shown no cross-reactivity with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.
特异性
The antibody neutralizes the biological activity of recombinant human OSM. Does not cross-react with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.
免疫原
recombinant human OSM expressed in Escherichia coli.
应用
Monoclonal anti-Oncostatin M antibody can be used in western blotting and capture ELISA.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (PBS) with 5% trehalose.
制备说明
Purified using protein A.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| EC 号 | 202-739-6 |
| MDL编号 | MFCD01092430 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 17001, monoclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable neutralization: suitable western blot: suitable |
| 同位素/亚型 | IgG2a |
| UniProt登记号 | P13725 |
| 储存温度 | −20℃ |
| Gene Information | human ... OSM(5008) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
