产品说明
一般描述
Inhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
Inhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
包装
5 mg in Plastic ampoule
生化/生理作用
Primary Target
MMP-3
Product does not compete with ATP.
Target IC50: 5 µM against MMP-3
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂
外形
Supplied as a trifluroacetate salt.
重悬
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
其他说明
Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C27H46N10O9S |
| 分子量 | 686.78 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥90% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 颜色 | white |
| 溶解性 | water: 1 mg/mL |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
