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Sumanirole Maleate-CAS 179386-44-8-Calbiochem

品牌
Sigma-Aldrich
CAS
179386-44-8
货号
5.05896
包装型号
规格纯度
参考价格
2280.72 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

An extremely selective dopamine D2 receptor agonist (Ki = 9 nM). Commonly used in Parkinson′s Disease models and to reproduce cocaine′s discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function.

警告

Toxicity: Standard Handling (A)

其他说明

Achat-Mendes, C. et al., 2010. J. Pharmacol. Exp. Ther.334, 556.
McCall, R. B. et al., 2005. J. Pharmacol. Exp. Ther.314, 1248.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C11H13N3O · xC4H4O4
分子量203.24 (free base basis)
MDL编号MFCD09832637

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
效能9 nM Ki
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 off-white
溶解性DMSO: 16 mg/mL
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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