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6,6′-Dithiodinicotinic acid

6,6′-二硫二烟酸

品牌
Sigma-Aldrich
CAS
15658-35-2
货号
373605
规格纯度
technical grade, 85%
参考价格
1123.32 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.

应用

6,6′-Dithiodinicotinic acid may be employed as:

  • specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
  • modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
  • dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
  • water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
  • chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
  • spectrophotometric determination of thiols and of total glutathione in human blood

包装

5 g in glass bottle

基本信息

经验(实验)分子式C12H8N2O4S2
分子量308.33
EC 号239-729-6
MDL编号MFCD00006454
PubChem化学物质编号24863248
NACRESNA.22

产品性质

等级technical grade
测定85%
mp263-265 ℃ (lit.)
SMILES stringOC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
InChI1S/C12H8N2O4S2/c15-11(16)7-1-3-9(13-5-7)19-20-10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
InChI keyGSASOFRDSIKDSN-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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