产品说明
一般描述
Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.
特异性
Antibody recognizes human PINK1.
免疫原
Recombinant protein corresponding to human PINK1.
应用
Milli-Mark Anti-PINK1-Alexa Fluor 488 Antibody, clone N4/49 is an antibody against PINK1-Alexa Fluor 488 for use in FC.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
质量
Evaluated by flow cytometry using HEK293 cells.
目标描述
Uniprot describes two isoforms exist with calculated Mw of 63 and 30 kDa
外形
Purified mouse monoclonal IgG1k conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein G Purified
储存及稳定性
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析说明
Control
HEK293 cells
法律信息
ALEXA FLUOR is a registered trademark of Life Technologies
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | ALEXA FLUOR® 488 |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | N4/49, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgG1κ |
| NCBI登记号 | NP_115785 |
| UniProt登记号 | Q9BXM7 |
| 运输 | wet ice |
| Gene Information | human ... PINK1(65018) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
