产品说明
一般描述
Human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and they are key components of germ cell tumors (GCTs). They express several high molecular weight glycoprotein antigens that are down-regulated upon differentiation. One of these antigens, defined by monoclonal antibody TRA-1-60, can be detected in the serum of GCT patients and provides a useful complement to the established serum markers human chorionic gonadotropin and α-fetoprotein, especially in those patients without elevated serum human chorionic gonadotropin or α-fetoprotein.
特异性
This antibody reacts with TRA-1-60 antigen expressed upon the surface of human EC, EG, and ES cells. No immunoreactivity is seen with murine EC, EG or ES cells. TRA-1-81 (MAB4381A4) and TRA-1-60 monoclonal antibodies recognize antigens that are associated with a pericellular matrix proteoglycan.
免疫原
Human embryonal carcinoma cell line 2102Ep
应用
Research Category
Neuroscience
Detect TRA-1-60 using this Anti-TRA-1-60 Antibody, clone TRA-1-60, Alexa Fluor 488 Conjugate validated for use in IC.
质量
Evaluated by Immunocytochemistry in H9 human embryonic stem cells.
Immunocytochemistry Analysis: A 1:200 dilution of this antibody detected TRA-1-60 in H9 human embryonic stem cells.
外形
Purified mouse monoclonal IgM conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
size exclusion
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
H9 human embryonic stem cells
法律信息
ALEXA FLUOR is a registered trademark of Life Technologies
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | ALEXA FLUOR® 488 |
| 抗体形式 | purified antibody |
| antibody product type | primary antibodies |
| 克隆 | TRA - 1-60, monoclonal |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable |
| 同位素/亚型 | IgM |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
