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Anti-MAP2, Alexa Fluor® 488 Conjugate Antibody

品牌
Sigma-Aldrich
货号
AB2290A4
规格纯度
from rabbit, ALEXA FLUOR® 488
参考价格
6861.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.

应用

This Anti-MAP2, Alexa Fluor 488 Conjugate Antibody is validated for use in ICC, IHC for the detection of MAP2.

质量

Evaluated by Immunocytochemistry in rat E18 cortex cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected MAP2 in rat E18 cortex cells.

目标描述

The unconjugated parent antibody (Cat. No. AB2290) has an observed molecular weight at ~260 kDa

外形

Affinity purified

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物ALEXA FLUOR® 488
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
species reactivityrat
technique(s)immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI登记号NP_037198
UniProt登记号P15146
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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