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Fibronectin human foreskin fibroblasts

纤连蛋白 溶液 来源于人类成纤维细胞

品牌
Sigma-Aldrich
货号
F2518
规格纯度
lyophilized powder, suitable for cell culture
参考价格
8986.89 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Fibronectin 1 (FN1) is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35. Fibronectin is mostly synthesized by fibroblasts and endothelial cells.

应用

Epithelial cells, mesenchymal cells, neuronal cells, fibroblasts, neural crest cells, endothelial cells
Fibronectin human foreskin fibroblasts has been used in extracellular matrix binding assay and probiglycan and cleavage assays. It has also been used in ectoderm (neuronal) differentiation and in the preparation of a semi-solid growth medium.

包装

0.5 mg in serum bottle

生化/生理作用

Fibronectin 1 (FN1) participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Fibronectin production by normal human foreskin fibroblasts has been shown to improve two-fold after glucocorticoid treatment.

注意

本品复原后,不建议涡漩、过度搅拌、反复冻融。

外形

Lyophilized in CAPS buffered saline

制备说明

dialyzed against chloroform

重悬

Store reconstituted solution in working aliquots at -20℃ or lower.

分析说明

蛋白质均一性由免疫电泳评估。

基本信息

EC 号289-149-2
MDL编号MFCD00131062
NACRESNA.75

产品性质

质量水平200
生物来源human foreskin fibroblasts
产品线BioReagent
形式lyophilized powder
分子量 ~550 kDa
包装pkg of 0.5 mg
technique(s)cell culture | mammalian: suitable
表面覆盖度 1‑5 μg/cm2
溶解性H2O: 1 mg/mL at 37 ℃ (Store reconstituted solution in working aliquots at -20℃ or lower.)
web metadata keyword.defaultattachment factor, mesenchymal cell attachment, neuronal cell attachment, fibroblast attachment, neural crest cell attachment, endothelial cell attachment
UniProt登记号P02751
运输dry ice
储存温度−20℃
Gene Informationhuman ... FN1(2335)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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