产品介绍：
产品说明
一般描述
化学结构:β-内酰胺
应用
细菌(金黄色葡萄球菌)β-内酰胺酶的有效抑制剂。
7-Aminocephalosporanic acid (7-ACA) can be used as a starting material to synthesize:
- Cefotaxime by acylation reaction with S-benzothiazol-2-yl(2-amino-4-thiazolyl)(methoxyimino)thioacetate (MAEM) in the presence of triethylamine.
- Cefpodoxime proxetil, a third-generation antibiotic via cefotaxime intermediate.
- Sodium 3′-substituted cephalosporanate sulfone derivatives as potential inhibitors of β-lactamase.
包装
5 g in glass bottle
基本信息
| 经验(实验)分子式 | C10H12N2O5S |
| 分子量 | 272.28 |
| Beilstein | 622637 |
| EC 号 | 213-485-0 |
| MDL编号 | MFCD00005177 |
| PubChem化学物质编号 | 24851470 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 200 |
| 测定 | 98% |
| 形式 | powder |
| 旋光性 | [α]19/D +90°, c = 0.5 in KH2PO4/trace NaOH |
| reaction suitability | reaction type: solution phase peptide synthesis |
| mp | >300 ℃ (lit.) |
| 抗生素抗菌谱 | Gram-positive bacteria |
| application(s) | peptide synthesis |
| 作用机制 | cell wall synthesis | interferes |
| 储存温度 | 2-8℃ |
| SMILES string | [H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2N)C(O)=O |
| InChI | 1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1 |
| InChI key | HSHGZXNAXBPPDL-HZGVNTEJSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H317 - H334 |
| 预防措施声明 | P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313 |
| 危险分类 | Resp. Sens. 1 - Skin Sens. 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
