产品说明
一般描述
Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .
特异性
The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.
免疫原
recombinant chicken plakoglobin.
应用
Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00164716 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | 15F11, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 85 kDa |
| 包含 | 15 mM sodium azide |
| species reactivity | canine, bovine, human |
| technique(s) | immunocytochemistry: suitable using cultured cells immunohistochemistry (frozen sections): suitable immunoprecipitation (IP): suitable indirect immunofluorescence: 1:1,000 using cultured MDBK cells microarray: suitable western blot: 1:2,000 using cultured MDBK cells |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P14923 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... JUP(3728) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
