产品说明
一般描述
C-reactive protein (CRP) is a member of the pentraxin family of proteins and synthesized by the liver. It is also known as PTX1. The CRP gene is mapped to human chromosome 1q23.2.
特异性
该抗体识别位于变性和还原 CRP 的 24 kDa 亚单位上的表位。与人血清淀粉样 P 成分 (SAP)、人结合珠蛋白、人 α1-酸性糖蛋白、人 IgG 和来自 鲎试剂的 CRP 不反应。
免疫原
人 C 反应蛋白。
应用
小鼠产生的单克隆抗 C 反应蛋白抗体适用于以下情况：
- 斑点印迹分析
- 工作稀释度为 1:40,000 的间接 ELISA
- 1:200 工作稀释液的免疫印迹法
- 已用于免疫印迹试验，以鉴别单体 CRP。
- 时间分辨荧光测定法。
生化/生理作用
C-reactive protein (CRP) shows essential scavenging and metabolic activity and is also associated with defence mechanism. It activates the complement pathway by binding to calcium-dependent exogenous and autologous molecules containing phosphocholine (PC). It may have pathogenic effects and is a practical prognostic marker in patients with hepatocellular carcinoma (HCC). The CRP diagnostic value is higher for acute pyelonephritis than lower urinary tract infection. Thus, it helps in differentiating between upper and lower urinary tract infection. It is considered best for predicting the risk of cardiovascular disease..
免责声明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或人类或动物应用。
基本信息
| MDL编号 | MFCD00162183 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | CRP-8, monoclonal |
| 分子量 | antigen 24 kDa |
| 包含 | 15 mM sodium azide |
| species reactivity | human |
| technique(s) | dot blot: suitable indirect ELISA: 1:40,000 western blot: 1:200 |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P02741 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CRP(1401) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
