产品说明
一般描述
A cell-permeable, reversible inhibitor of nitric oxide synthase in vitro (IC50 = 2-3 µM) and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
Endogenous reversible inhibitor of nitric oxide synthesis in vitro and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
包装
25 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Primary Target
NOS in vitro
Target IC50: 2-3 µM inhibiting nitric oxide synthase in vitro
Product does not compete with ATP.
Reversible: yes
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
其他说明
Closs, E.I., et al. 1997. Nitric Oxide1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol.269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.
Vallance, P., et al. 1992. Lancet339, 572.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C8H18N4O2 · 2HCl |
| 分子量 | 275.18 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (TLC) |
| 形式 | amorphous solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 颜色 | white |
| 溶解性 | water: 50 mg/mL |
| 运输 | wet ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
