产品说明
一般描述
Monoclonal anti-Cytokeratin Peptide 18 (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
特异性
The antibody reacts with a wide variety of simple epithelia (gastrointestinal, respiratory, urinary, liver, and glandular) but does not react with most stratified squamous epithelium (esophagus, epidermis) or non-epithelial cells.
免疫原
keratin from the bovine mammary gland epithelial cell line BMGE.
应用
Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse has been used in:
- immunofluorescence
- immunoperoxidase staining
- immunocytochemistry
- microarray
生化/生理作用
Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00162250 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | KS-B17.2, monoclonal |
| 包含 | 15 mM sodium azide |
| species reactivity | human |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable indirect immunofluorescence: 1:100 using formalin-fixed, paraffin-embedded sections of human tissue microarray: suitable |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P05783 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KRT18(3875) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
