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Anti-Chloride Channel-2 (CLC-2, Clcn2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
C9477
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

synthetic peptide corresponding to amino acids 888-906 of the rat chloride channel-2 (CLC-2).

应用

Anti-Chloride Channel-2 antibody produced in rabbit is suitable for western blot (chemiluminescent) at a working dilution of 1:200-1:400 using rat membranes and ECL.

生化/生理作用

The encoded protein, voltage-gated chloride channel, is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Autosomal-recessive mutations ion this gene cause a leukoencephalopathy that affects brain ion and water homoeostasis. It is characterized by intramyelinic oedema. It is involved in maintaining the volume of trabecular meshwork cells by adjusting the outflow of aqueous solutions and for maintaining the fluid balance. It may be a potential target for the treatment of primary open angle glaucoma.

外形

Lyophilized at ~0.6 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.025% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02096079
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityrat
technique(s)western blot (chemiluminescent): 1:200-1:400 using rat membranes and ECL
UniProt登记号P35525
储存温度−20℃
Gene Informationrat ... Clcn2(29232)

Sigma-Aldrich

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