产品说明
一般描述
Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.
特异性
Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15INK4b, p16INK4a and p18INK4c.
免疫原
recombinant human p19INK4d.
应用
Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.
生化/生理作用
Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01324442 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | DCS-100, monoclonal |
| 分子量 | antigen 19 kDa |
| 包含 | 15 mM sodium azide |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable immunoprecipitation (IP): suitable microarray: suitable western blot: 1:1,000 using a cultured human tumor cell line extract |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P55273 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CDKN2D(1032) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
