产品介绍：
产品说明
一般描述
1-Bromo-4-chloro-2-fluorobenzene is a polyhalo substituted benzene. It undergoes Suzuki coupling with 2-cyanoarylboronic esters to form the corresponding biphenyls. These biphenyls are the precursors for synthesizing 6-substituted phenanthridines.† The enthalpy of vaporization at boiling point (467.15K) of 1-bromo-4-chloro-2-fluorobenzene is 40.737kjoule/mol.{4}
应用
1-Bromo-4-chloro-2-fluorobenzene may be used in the preparation of benzonorbornadiene derivative. It may also be used as a starting material in the multi-step synthesis of AZD3264, an IKK2 (inhibitor of nuclear factor κ-B kinase-2) inhibitor.
包装
25 g in glass bottle
基本信息
| 线性分子式 | BrC6H3(Cl)F |
| 分子量 | 209.44 |
| MDL编号 | MFCD00079708 |
| PubChem化学物质编号 | 24877906 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 200 |
| 测定 | 98% |
| 折射率 | n |
| bp | 91-92 ℃/20 mmHg (lit.) |
| 密度 | 1.678 g/mL at 25 ℃ (lit.) |
| SMILES string | Fc1cc(Cl)ccc1Br |
| InChI | 1S/C6H3BrClF/c7-5-2-1-4(8)3-6(5)9/h1-3H |
| InChI key | FPNVMCMDWZNTEU-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 198.0 °F - closed cup |
| 闪点(C) | 92.2 ℃ - closed cup |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
