产品说明
一般描述
2-Fluorobenzoyl chloride reacts with ethyl 5-amino-1-methylpyrazole-4-carboxylate to give N-mono-N,N-di-substituted intermediate which on ring closure yields heteroannulated oxazinone.
应用
2-Fluorobenzoyl chloride has been used in the preparation of 3-(N-Hydroxycarbamimidoyl)-benzoic acid methyl ester. It has been used to develop an hollow-fiber liquid phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids.
包装
25, 100 g in glass bottle
基本信息
线性分子式 | FC6H4COCl |
分子量 | 158.56 |
Beilstein | 636864 |
EC 号 | 206-887-2 |
MDL编号 | MFCD00000656 |
PubChem化学物质编号 | 24847433 |
NACRES | NA.22 |
产品性质
质量水平 | 200 |
测定 | 99% |
折射率 | n |
bp | 90-92 ℃/15 mmHg (lit.) |
mp | 4 ℃ (lit.) |
密度 | 1.328 g/mL at 25 ℃ (lit.) |
SMILES string | Fc1ccccc1C(Cl)=O |
InChI | 1S/C7H4ClFO/c8-7(10)5-3-1-2-4-6(5)9/h1-4H |
InChI key | RAAGZOYMEQDCTD-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H314 |
预防措施声明 | P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
危险分类 | Skin Corr. 1B |
储存分类代码 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |
闪点(F) | 251.6 °F - closed cup |
闪点(C) | 122 ℃ - closed cup |
个人防护装备 | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |