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Anti-Collagen Type III antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200749
规格纯度
clone FH-7A, purified from hybridoma cell culture
参考价格
6732.28 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Anti-collagen type III antibody, mouse monoclonal (mouse IgG1 isotype) is derived from the FH-7A hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c immunized mouse.
Monoclonal anti-collagen type III specifically recognizes native and denatured collagen type III from human 1 and rat 2 origin. It does not recognize collagen types I, II, IV, V, VI and X.
Collagen type III, also known as collagen α-1(III) (COL3A1), is encoded by the gene mapped to human chromosome 2q24.3-q31. It is the highly expressed collagen in blood vessels and hollow organs.

免疫原

Human Collagen Type III

生化/生理作用

Collagen a-1(III) (COL3A1) serves as a potent adjunct marker for both differentiating fibroadenoma (FA) from phyllodes tumor (PT) and measuring malignant potential in PTs. Overexpression of the gene in glomerular leads to the development of collagen type III glomerulopathy. Mutations in the gene is associated with the development of familial aortic aneurysms and Ehlers-Danlos syndrome.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

储存及稳定性

Store at -20℃. For continuous use, store at 2-8℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

其他说明

In order to obtain best results in different techniques and preparations we recommend determining optimal working concentration by titration test.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆FH-7A, monoclonal
形式buffered aqueous solution
分子量 ~70 kDa
species reactivityhuman, rat
浓度~1.0 mg/mL
technique(s)ELISA: suitable
immunoblotting: suitable
immunofluorescence: suitable
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded rat skin sections.
同位素/亚型IgG1
UniProt登记号P02461
运输dry ice
储存温度−20℃
Gene Informationhuman ... COL3A1(1281)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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