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Monoclonal Anti-Mad1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
M8069
规格纯度
~2 mg/mL, clone 9B10, purified immunoglobulin, buffered aqueous solution
参考价格
8285.36 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monoclonal Anti-Mad1 (mouse IgG2b isotype) is derived from the hybridoma 9B10 produced by the fusion of mouse myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with human recombinant Mad1 protein.
Mitotic arrest deficient-like 1 (MAD1) is part of the cell-cycle checkpoint.

免疫原

recombinant human Mad1 protein.

应用

Monoclonal Anti-Mad1 antibody produced in mouse has been used in

  • immunoblotting
  • immunoprecipitation
  • immunocytochemistry

生化/生理作用

Mitotic arrest deficient-like 1 (MAD1) functions as a regulator in the segregation of chromosomes during mitosis. It recruits mitotic arrest deficient-like 2 (MAD2) to kinetochores and directs it to function as an inhibitor. MAD1 also helps MAD2 to associate with translocated promoter region (TPr).

外形

Solution in 0.01 M phosphae buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD08705588
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆9B10, monoclonal
形式buffered aqueous solution
分子量antigen ~85 kDa
species reactivityhuman
浓度~2 mg/mL
technique(s)immunocytochemistry: 10-20 μg/mL using HeLa cells
immunoprecipitation (IP): suitable
microarray: suitable
同位素/亚型IgG2b
UniProt登记号Q9Y6D9
运输dry ice
储存温度−20℃
Gene Informationhuman ... MAD1L1(8379)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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