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Anti-SOX2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
S9072
规格纯度
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
参考价格
4349.44 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Transcription factor SOX-2 (SOX-2) is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. When SOX-2 is expressed in self renewing progenitor cells, it acts to inhibit neuronal differentiation. Conversely, active repression of SOX-2 induces neural differentiation.

特异性

Rabbit polyclonal anti-SOX2 antibody recognizes human, mouse, rat sex-determining region Y-box 2 transcription factors.

免疫原

synthetic peptide corresponding to residues 32-47 of human SOX2.

应用

Rabbit polyclonal anti-SOX2 antibody is used to tag solute sex-determining region Y-box 2 transcription factor for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques, such as immunoblotting (~37 kDa) and flow cytometry. It is used as a probe to determine the presence and roles of sex-determining region Y-box 2 transcription factor in progenitor cell self renewal and differentiation.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)

外形

solution in phosphate buffered saline, containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD03097285
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 34-37 kDa
species reactivityhuman, mouse, rat
浓度~1 mg/mL
technique(s)flow cytometry: 1:200-1:500
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000
UniProt登记号P48431
运输dry ice
储存温度−20℃
Gene Informationhuman ... SOX2(6657)
mouse ... Sox2(20674)
rat ... Sox2(499593)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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