Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse

产品说明

一般描述

Cytokeratins also known as keratins are filament-forming proteins of epithelial cells. In humans, there are 54 cytokeratins. These proteins are divided in to two sub-categories such as acidic type I keratins and basic-to-neutral type II keratins.
The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

免疫原

Keratin-enriched preparation from human epidermoid carcinoma cell line A431

应用

Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse has been used in immunocytochemistry.
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

生化/生理作用

Cytokeratins play an essential role in normal tissue structure and function. It also facilitates the maintenance of cell mechanical integrity.

特点和优势

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外形

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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