产品说明
应用
Phosphocreatine disodium salt hydrate has been used:
- as a component: of Xenopus buffer (XB) buffer to remove the membrane-bound proteins
- of M5+ buffer to perform polarized total internal reflection fluorescence (polTIRF) experiments
- of ATP regenerating system for 7-nitro-2-1,3-benzoxadiazol-4-yl phospholipid(NBD-PL) translocation assay
包装
10 mg in glass bottle
1, 5, 25 g in poly bottle
生化/生理作用
Phosphocreatine is widely known for its quickest form of regeneration using enzyme creatine kinase. It functions as a temporal energy buffer. Phosphocreatine is present in muscle tissues and plays a major role in maintaining energy homeostasis in muscle cells.
Phosphocreatine, a high-energy phosphate reservoir in vertebrate and some invertebrate muscles, provides phosphate for ADP-ATP conversion.
Phosphocreatine disodium salt hydrate is useful to study nasopharyngeal carcinoma cells and induced temporary cardiac arrest. It also evaluate the effects of adenosine A(2A) receptor modulation in the nucleus accumbens on cocaine seeking in rats.
制备说明
酶法制备。
基本信息
| 线性分子式 | C4H8N3O5PNa2 · x H2O |
| 分子量 | 255.08 (anhydrous basis) |
| EC 号 | 213-074-6 |
| MDL编号 | MFCD00150191 |
| PubChem化学物质编号 | 24898895 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥97% |
| 形式 | powder |
| 杂质 | ≤0.02% free creatine |
| 颜色 | white |
| 溶解性 | water: 50 mg/mL, clear, colorless |
| 储存温度 | −20℃ |
| SMILES string | O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O |
| InChI | 1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2 |
| InChI key | KZVYPOKBYRXZKS-UHFFFAOYSA-L |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
