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6-Methylmercaptopurine riboside

品牌
Sigma-Aldrich
CAS
342-69-8
货号
M4002
包装型号
规格纯度
≥99% (HPLC)
参考价格
4058.33 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition.
6-Methylmercaptopurine riboside (6MMPR) has been used as a phosphoribosyl pyrophosphate amidotransferase inhibitor to study its effects on DNA replication in a retinoblastoma (Rb) phosphorylation-independent manner in human cytomegalovirus (HCMV) , as a purine analog to determine its effects on angiogenesis of endothelial cells induced by fibroblast growth factor 2 (FGF2) in vitro and in vivo, as a metabolite of 6-methylmercaptopurine to determine its levels in human plasma by high-performance liquid chromatography (HPLC) method .

包装

1 g in poly bottle

生化/生理作用

6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N.

基本信息

经验(实验)分子式C11H14N4O4S
分子量298.32
EC 号206-442-2
PubChem化学物质编号24896894

产品性质

质量水平200
生物来源synthetic (organic)
测定≥99% (HPLC)
形式powder
溶解性methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度−20℃
SMILES stringO[C@H]([C@@H](CO)O1)[C@@H](O)[C@@H]1N2C=NC3=C(SC)N=CN=C32
InChI1S/C11H14N4O4S/c1-20-10-6-9(12-3-13-10)15(4-14-6)11-8(18)7(17)5(2-16)19-11/h3-5,7-8,11,16-18H,2H2,1H3
InChI keyZDRFDHHANOYUTE-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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