产品说明
一般描述
γ-Globulins are immunoglobulins and occur in five classes, namely: IgG, IgM, IgA, IgD, and IgE. These are glycoproteins that are antibodies produced by plasma cells. The immunoglobulins are heterogeneous molecules made up of four polypeptide chains (two light chains and two heavy chains) linked together by disulfide bonds. The antigen-binding site is present at the nitrogen terminal. 20% of the protein in plasma are immunoglobulins.
应用
γ-Globulins from human blood have been used for the blocking step in cytometric bead array It has also been used as a standard for γ-globulin measurement in cerebrospinal fluid (CSF).
γ-球蛋白已用于研究微量滴定板孔中苄索氯铵测定脑脊液中总蛋白的方法。它用于使用茚三酮测定单宁-蛋白质沉淀物中的蛋白质。它也用于研究左西替利嗪(一种新型的非镇静组胺 H1 受体拮抗剂)在人体中的血液分布。
包装
250 mg in poly bottle
1, 5, 10, 25 g in poly bottle
生化/生理作用
Immunoglobulins are key regulators of the immune system and are produced in response to antigens. They protect our bodies against bacteria, viruses, and fungi. Immunoglobulins are involved in the activation of the complement system, opsonization of microbes for phagocytosis, neutralization of toxins and viruses, and inhibition of the attachment of microbes to mucosal surfaces. Immunodeficiency can lead to recurrent infectious diseases.
制备说明
从科恩级分 II、 III 制备
基本信息
| MDL编号 | MFCD00164089 |
| NACRES | NA.61 |
产品性质
| 质量水平 | 300 |
| 生物来源 | human blood |
| 测定 | ≥99% (electrophoresis) |
| 形式 | powder |
| technique(s) | protein quantification: suitable |
| 杂质 | HIV, HCV and HBsAg, source material tested negative ≤4% NaCl |
| 溶解性 | 0.9% NaCl: soluble 50 mg/mL |
| UniProt登记号 | P15814 |
| 储存温度 | 2-8℃ |
| Gene Information | human ... IGLL1(3543) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
