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5-Methoxy-L-tryptophan

品牌
Sigma-Aldrich
CAS
25197-96-0
货号
SMB00930
规格纯度
98-102%
参考价格
1759.1 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

5-Methoxy-L-tryptophan is a L-tryptophan metabolite that exhibits anti-inflammatory and tumor-suppressing activities. 5-Methoxy-L-tryptophan is synthesized by tryptophan hydroxylase (TPH) and hydroxyindole O-methyltransferase (HIOMT). Recent study indicates 5-methoxytryptophan as a biomarker of progression of chronic kidney disease (CKD). Its levels decrease during disease and treatment with 5-methoxytryptophan ameliorates kidney fibrosis n mice model of CKD. 5-Methoxytryptophan appears to inhibit I?B/NF-?B signaling and enhaces Keap1/Nrf2 signaling in mice model of unilateral ureteral obstruction. Literature often uses the name 5-Methoxytryptophan instead L-5-Methoxytryptophan.

基本信息

经验(实验)分子式C12H14N2O3
分子量234.25

产品性质

质量水平100
测定98-102%
形式solid
旋光性[α]20/D -30 to -28° in water
颜色 off-white to light yellow
储存温度2-8℃

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310 + P330
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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