产品说明
一般描述
Absorbance (10%, H2O, 290 nm):≤0.25.
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state (absorbance: <0.25 at 290 nm, 10% H2O; aggregation number: 3-12; CMC: 2-6 mM; micellar weight: 1200-4900; pKa: 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12.
包装
5, 25 g in Glass bottle
警告
Toxicity: Harmful (C)
制备说明
Do not use with Mn2+ in solution.
重悬
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. Discard if bacterial or fungal growth is observed.
其他说明
Pai, R., et al. Mol. Biol. Cell15, 2156.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C24H39NaO4 |
| 分子量 | 414.55 |
| Beilstein | 3581950 |
| MDL编号 | MFCD00064139 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥99% (TLC) |
| 形式 | solid |
| 分子量 | micellar avg mol wt 1200-5000 micellar wt 1200-4900 |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 聚集数 | 3 - 12 3-12 |
| 颜色 | white |
| pKa | 6.2 |
| CMC | 2 - 6 mM 2-6 mM (20-25℃) |
| HLB | 16 |
| 运输 | ambient |
| 储存温度 | 15-25℃ |
| SMILES string | [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2 |
| InChI | 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1 |
| InChI key | FHHPUSMSKHSNKW-SMOYURAASA-M |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P264 - P270 - P301 + P312 - P501 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
