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Acylase I from porcine kidney

酰基酶Ⅰ 来源于猪肾脏

品牌
Sigma-Aldrich
CAS
9012-37-7
货号
A8376
规格纯度
Grade II, salt-free, lyophilized powder, 500-1,500 units/mg protein
参考价格
2558.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .

包装

1, 10 g in poly bottle

生化/生理作用

Acylase I is a zinc metalloprotein that catalyzes the kinetic resolution of unnatural and rarely occurring α-amino acids. Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality. Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates.

单位定义

One unit will hydrolyze 1.0 μmole of N-acetyl-L-methionine per hr at pH 7.0 at 25 ℃.

分析说明

Protein determined by biuret.

基本信息

酶学委员会(EC)编号3.5.1.14 ( BRENDA | IUBMB )
EC 号232-732-3
MDL编号MFCD00081285
NACRESNA.54

产品性质

质量水平200
类型Grade II
形式salt-free, lyophilized powder
specific activity500-1,500 units/mg protein
UniProt登记号P37111
储存温度−20℃
Gene Informationpig ... ACY1(396930)

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H319 - H334 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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