产品说明
一般描述
6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.
应用
6-(Dimethylamino)purine has been used:
- as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development
- in the activation step during the production of nuclear transfer embryos
- as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique
包装
100, 250, 500 mg in poly bottle
1 g in poly bottle
生化/生理作用
6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.
其他说明
斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF D2629.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。
基本信息
| 经验(实验)分子式 | C7H9N5 |
| 分子量 | 163.18 |
| Beilstein | 7634 |
| EC 号 | 213-344-3 |
| MDL编号 | MFCD00005573 |
| PubChem化学物质编号 | 24893701 |
产品性质
| 生物来源 | synthetic (organic) |
| 质量水平 | 100 |
| 测定 | ≥98% |
| 形式 | powder |
| mp | 259-262 ℃ (lit.) |
| 溶解性 | water: 50 mg/mL, clear to hazy, colorless to light yellow |
| 储存温度 | −20℃ |
| SMILES string | CN(C)c1ncnc2[nH]cnc12 |
| InChI | 1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11) |
| InChI key | BVIAOQMSVZHOJM-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
