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hTDRD4 (30-139) human

品牌
Sigma-Aldrich
货号
SRP6277
规格纯度
recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
参考价格
3983.18 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The Tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The Tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. TDRD4 is a candidate CT antigen expressed in a subset of liver cancers. The recombinant protein includes TDRD4 (domain 30-139 aa) with N-terminal His-tag.

外形

1.0 mg/mL solution in 25 mM Tris (pH 8.0) buffer containing 20% glycerol.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥98% (SDS-PAGE)
形式liquid
分子量 14.6 kDa (110 aa + NT 6 x His-tag)
包装pkg of 1 mg
pkg of 100 μg
pkg of 20 μg
浓度1 mg/mL
UniProt登记号Q9BXT8
运输dry ice
储存温度−70℃
Gene Informationhuman ... TDRD4(56163)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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