产品说明
一般描述
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) is a trypsin substrate. It is more water-soluble than 4-methylumbelliferyl 4-guanidinobenzoate and is preferred in spectrophotometric assay.
应用
4-Nitrophenyl 4-guanidinobenzoate hydrochloride has been used:
- as a substrate for trypsin for active site titration experiments
- for pre-treating of mosquito eggs in the interplasmid transposition assay
- as a component of isotonic buffer to moisten filter paper for mosquito embryo collection
包装
1 g in glass bottle
500 mg in glass bottle
生化/生理作用
4-Nitrophenyl 4-guanidinobenzoate hydrochloride (pNPGB) inhibits phenoloxidase enzyme and delays embryo chorionic membrane hardening.
基本信息
经验(实验)分子式 | C14H12N4O4 · HCl |
分子量 | 336.73 |
Beilstein | 8024554 |
EC 号 | 242-831-3 |
MDL编号 | MFCD00037010 |
PubChem化学物质编号 | 24897847 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
测定 | ≥95.0% (TLC) |
形式 | powder |
溶解性 | formic acid: soluble 49.00-51.00 mg/mL |
储存温度 | −20℃ |
SMILES string | Cl[H].NC(=N)Nc1ccc(cc1)C(=O)Oc2ccc(cc2)[N+]([O-])=O |
InChI | 1S/C14H12N4O4.ClH/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21;/h1-8H,(H4,15,16,17);1H |
InChI key | PKSBDZOBYIKNGY-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H318 |
预防措施声明 | P280 - P305 + P351 + P338 |
危险分类 | Eye Dam. 1 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |