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Mycophenolic Acid-CAS 24280-93-1-Calbiochem

麦考酚酸-CAS 24280-93-1-Calbiochem

品牌
Sigma-Aldrich
CAS
24280-93-1
货号
475913
规格纯度
An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP.
参考价格
1582.44 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of IMP dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.

包装

100, 500 mg in Plastic ampoule

生化/生理作用

Primary Target
Inosine monophosphate dehydrogenase
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Langman, L.J., et al. 1995. Clin. Chem. 41, 295.
Senda, M., et al. 1995. Transplantation60, 1143.
Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res.204, 241.
Falkner, F.G., and Moss, B. 1988. J. Virol.62, 1849.
Cohen, M.B., et al. 1981. J. Biol. Chem.256, 8713.
Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA78, 2072.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C17H20O6
分子量320.34
MDL编号MFCD00036814

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white to off-white
溶解性0.1 M NaOH: 10 mg/mL
ethanol: soluble
运输ambient
储存温度10-30℃
InChI1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
InChI keyHPNSFSBZBAHARI-RUDMXATFSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H341 - H360D - H372 - H410
预防措施声明P201 - P202 - P260 - P273 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Repr. 1B - STOT RE 1 Oral
靶器官Immune system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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